Document Detail

Analysis of risk factors influencing imminent distress in growth-retarded fetuses undergoing oxygen test.
MedLine Citation:
PMID:  8373907     Owner:  NLM     Status:  MEDLINE    
We previously demonstrated a prognostic significance of maternal oxygen test in predicting imminent fetal distress. The purpose of this study was to investigate eventual other factors related to the length of the time interval elapsing between the Doppler diagnosis of brain sparing effect and abnormal fetal heart rate patterns. To this end we considered 101 growth-retarded fetuses free of structural and chromosomal abnormalities with a ratio between the pulsatility indices of umbilical and middle cerebral artery above the 95th centile in presence of a normal fetal heart rate pattern. The factors, other than the oxygen test, analyzed for a potential influence on this time interval were gestational age, presence of hypertension or preeclampsia, amniotic fluid index, severity of growth retardation (centile of the ultrasonographic estimated fetal weight) and 9 different Doppler indices calculated from extra- and intracardiac districts. Statistical actuarial methods were used to determine the effect of these prognostic factors on the duration of this time interval. The occurrence of abnormal fetal heart rate patterns (antepartum late heart rate decelerations) was used as censoring variable. The time interval between the entry in the study and delivery ranged from 1 to 39 days. Indications for delivery were fetal distress in 53 fetuses (52.4%) and different maternal or fetal complications in the remaining 48 fetuses.(ABSTRACT TRUNCATED AT 250 WORDS)
D Arduini; G Rizzo; G G Garzetti; C Romanini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  63     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1993  
Date Detail:
Created Date:  1993-10-21     Completed Date:  1993-10-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  341-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Ancona, Italy.
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MeSH Terms
Fetal Distress / diagnosis*,  etiology
Fetal Growth Retardation / complications*
Fetal Monitoring
Fetus / blood supply
Gestational Age
Heart Rate, Fetal / drug effects
Hemodynamics / drug effects
Maternal-Fetal Exchange
Multivariate Analysis
Oxygen / pharmacology
Prenatal Diagnosis*
Risk Factors
Ultrasonography, Prenatal
Reg. No./Substance:

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