Document Detail

Analysis of research studying the effects of polychlorinated biphenyls and related chemicals on neurobehavioral development in children.
MedLine Citation:
PMID:  11474738     Owner:  NLM     Status:  MEDLINE    
During the past 25 y numerous studies have been performed in infants and children to determine whether environmental exposure to polychlorinated biphenyls (PCBs), dibenzo-p-dioxins, dibenzofurans (PCDFs) and dichlorodiphenyl trichloroethane is causally associated with neurobehavioral effects. In addition, 1 episode of poisoning with PCDFs occurred in Taiwan in 1978. This poisoning outbreak is referred to as Yu-Cheng, oil disease, since the PCDFs and PCBs had accidentally contaminated cooking oil. In the aggregate the studies reviewed here show no conclusive evidence that environmental exposure to these chemicals affect the neurobehavioral development of infants and children.
R D Kimbrough; M L Doemland; C A Krouskas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Veterinary and human toxicology     Volume:  43     ISSN:  0145-6296     ISO Abbreviation:  Vet Hum Toxicol     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-27     Completed Date:  2001-12-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7704194     Medline TA:  Vet Hum Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  220-8     Citation Subset:  IM    
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MeSH Terms
Child Behavior / drug effects*,  physiology
Child, Preschool
Environmental Exposure / adverse effects*
Environmental Pollutants / adverse effects*
Nervous System / drug effects*
Nervous System Physiological Phenomena
Neuropsychological Tests*
Polychlorinated Biphenyls / adverse effects*
Reg. No./Substance:
0/Environmental Pollutants; 0/Polychlorinated Biphenyls

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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