| Analysis of quality of life data from a randomized, placebo-controlled heart-failure trial. | |
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MedLine Citation:
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PMID: 2681547 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a randomized, double-blind, placebo-controlled, 3-months trial involving 111 congestive heart failure patients, one non-validated and three validated Quality of Life (QL) instruments were administered. Two randomized treatment groups were evaluated, one with 62 patients who continued on standard therapy and the other with 49 patients whose standard therapy was replaced by placebo. The data from Patient's Self-rating Scale (a non-validated instrument) and Spitzer's QL index showed a significant difference between the two treatment groups for an overall effect. There were no significant differences between two treatment groups for Sickness Impact Profile (SIP) and Quality of Well-Being (QWB). For analyzing the multiple components in a QL instrument, the global statistics as suggested by O'Brien were applied to compare the two treatment groups. Univariate statistics complemented the global methods. The general use of global statistics in analyzing QL data is recommended. |
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Authors:
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P K Tandon; H Stander; R P Schwarz |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Journal of clinical epidemiology Volume: 42 ISSN: 0895-4356 ISO Abbreviation: J Clin Epidemiol Publication Date: 1989 |
Date Detail:
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Created Date: 1989-11-30 Completed Date: 1989-11-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8801383 Medline TA: J Clin Epidemiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 955-62 Citation Subset: IM |
Affiliation:
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Sterling Research Group, Rensselaer, NY 12144. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Data Interpretation, Statistical Double-Blind Method Exercise Test Female Heart Failure / drug therapy*, psychology Humans Male Middle Aged Quality of Life* Randomized Controlled Trials as Topic Self Assessment (Psychology) |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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