Document Detail


Analysis of oocyte cryopreservation in assisted reproduction: the Italian National Register data from 2005 to 2007.
MedLine Citation:
PMID:  20797902     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper reports on oocyte cryopreservation efficacy in Italy with respect to successful IVF from 2005 to 2007, presenting data from 193 centres collected by the Italian National Register. Post-thawing survival rates, number of transferred embryos, implantation rates and clinical pregnancy rates per transfer with respect to frozen/vitrified oocytes (FVO) were analysed. These numbers were compared with those obtained using frozen embryos or fresh oocytes. A total of 121,708 cycles were initiated, of which, 7.1% (8682) were FVO cycles and 2.4% (2952) were frozen embryo cycles. Of the 81,786 FVO, 52.5% (42,917) were thawed and 26.9% (22,005) inseminated. Of those inseminated, 68.0% (14,966) yielded good embryos. These numbers were significantly lower than those using fresh oocytes in which 77.9% (197,242; fresh oocytes versus FVO P<0.001) of inseminated oocytes generated good embryos. Implantation rate using FVO was 6.9%, which was significantly lower than that using fresh oocytes (13.5%; P<0.001) and frozen embryos (8.8%; P<0.001). Pregnancy rate per transfer using FVO was 12.5% and significantly lower than that using fresh oocytes (24.9%; P<0.001) or frozen embryos (16.4%; P<0.001). There were 505 deliveries after IVF with FVO and 582 babies.
Authors:
G Scaravelli; V Vigiliano; J M Mayorga; S Bolli; R De Luca; P D'Aloja
Publication Detail:
Type:  Journal Article; Multicenter Study     Date:  2010-05-24
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  21     ISSN:  1472-6491     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  496-500     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
Affiliation:
ART Italian National Register, National Centre for Epidemiology, Surveillance and Health Promotion, Istituto Superiore di Sanità, 00161 Rome, Italy. giulia.scaravelli@iss.it
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MeSH Terms
Descriptor/Qualifier:
Congenital Abnormalities / epidemiology
Cryopreservation / methods*
Embryo Implantation
Embryo Transfer / methods*
Female
Fertilization in Vitro
Freezing
Humans
Italy / epidemiology
Oocytes*
Pregnancy
Pregnancy Rate
Vitrification*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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