| Analysis of oocyte cryopreservation in assisted reproduction: the Italian National Register data from 2005 to 2007. | |
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MedLine Citation:
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PMID: 20797902 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper reports on oocyte cryopreservation efficacy in Italy with respect to successful IVF from 2005 to 2007, presenting data from 193 centres collected by the Italian National Register. Post-thawing survival rates, number of transferred embryos, implantation rates and clinical pregnancy rates per transfer with respect to frozen/vitrified oocytes (FVO) were analysed. These numbers were compared with those obtained using frozen embryos or fresh oocytes. A total of 121,708 cycles were initiated, of which, 7.1% (8682) were FVO cycles and 2.4% (2952) were frozen embryo cycles. Of the 81,786 FVO, 52.5% (42,917) were thawed and 26.9% (22,005) inseminated. Of those inseminated, 68.0% (14,966) yielded good embryos. These numbers were significantly lower than those using fresh oocytes in which 77.9% (197,242; fresh oocytes versus FVO P<0.001) of inseminated oocytes generated good embryos. Implantation rate using FVO was 6.9%, which was significantly lower than that using fresh oocytes (13.5%; P<0.001) and frozen embryos (8.8%; P<0.001). Pregnancy rate per transfer using FVO was 12.5% and significantly lower than that using fresh oocytes (24.9%; P<0.001) or frozen embryos (16.4%; P<0.001). There were 505 deliveries after IVF with FVO and 582 babies. |
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Authors:
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G Scaravelli; V Vigiliano; J M Mayorga; S Bolli; R De Luca; P D'Aloja |
Publication Detail:
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Type: Journal Article; Multicenter Study Date: 2010-05-24 |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 21 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-27 Completed Date: 2011-01-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: Netherlands |
Other Details:
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Languages: eng Pagination: 496-500 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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ART Italian National Register, National Centre for Epidemiology, Surveillance and Health Promotion, Istituto Superiore di Sanità, 00161 Rome, Italy. giulia.scaravelli@iss.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Congenital Abnormalities
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epidemiology Cryopreservation / methods* Embryo Implantation Embryo Transfer / methods* Female Fertilization in Vitro Freezing Humans Italy / epidemiology Oocytes* Pregnancy Pregnancy Rate Vitrification* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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