Document Detail


Analysis of the microenvironment necessary for engraftment: role of the vascular smooth muscle-like stromal cells.
MedLine Citation:
PMID:  11177608     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is a review of recent data concerning the phenotype of human and murine stroma, as grown in long-term cultures. Using data on cytoskeletal and extracellular matrix protein expression, a sequential model of differentiation from mesenchymal (stem) cells to vascular-smooth muscle-like stromal cells is proposed. This model would apply, at least in the mouse, to stromal cells generated from different sites of hematopoiesis (bone marrow, fetal liver, spleen, and yolk sac). The in vivo counterparts of vascular-smooth muscle-like stromal cells in the different sites of definitive hematopoiesis are discussed.
Authors:
P Charbord; J P Rémy-Martin; E Tamayo; G Bernard; A Keating; B Péault
Related Documents :
24286758 - Bone marrow-derived stem cells and hepatocarcinogenesis in hepatitis b virus transgenic...
24092748 - Therapeutic efficacy of human embryonic stem cell-derived endothelial cells in humanize...
24292708 - Aptamer-targeted inhibition of mtor in t cells enhances antitumor immunity.
23889118 - Chinese box turtle (cuora flavomarginata) with lymphoid leukemia characterized by immun...
15621778 - Angiopoietin-1 and myeloma-induced angiogenesis.
20422368 - Comparison of ganglioside expression between human adipose- and dental pulp-derived ste...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of hematotherapy & stem cell research     Volume:  9     ISSN:  1525-8165     ISO Abbreviation:  J. Hematother. Stem Cell Res.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-06-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100892915     Medline TA:  J Hematother Stem Cell Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  935-43     Citation Subset:  IM    
Affiliation:
ETS de Franche Comté, Besançon, France. charbord@vjf.inserm.fr
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Graft Survival / physiology*
Hematopoiesis
Hematopoietic Stem Cell Transplantation
Humans
Mice
Muscle, Smooth, Vascular / cytology
Stromal Cells / cytology*,  metabolism,  physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  In vitro culture of human acute myelogenous leukemia (AML) cells in serum-free media: studies of nat...
Next Document:  Negative influence of IL3 on the expansion of human cord blood in vivo long-term repopulating stem c...