Document Detail


Analysis of the interactions of a cationic surfactant (lauric arginate) with an anionic biopolymer (pectin): isothermal titration calorimetry, light scattering, and microelectrophoresis.
MedLine Citation:
PMID:  19067576     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lauric arginate (LAE), a cationic surfactant, is a highly potent food-grade antimicrobial that is active against a wide range of food pathogens and spoilage organisms. In compositionally complex environments, the antimicrobial activity of cationic LAE is likely to be impacted by its interactions with anionic components. The purpose of this study was to characterize the interactions between cationic LAE and an anionic biopolymer (high methoxyl pectin, HMP) using isothermal titration calorimetry (ITC), microelectrophoresis (ME), and turbidity measurements. ITC and ME measurements indicated that LAE bound to pectin, while turbidity measurements indicated that the complexes formed could be either soluble or insoluble depending on solution composition. In the absence of pectin, the critical micelle concentration (CMC) of LAE determined by ITC at 25 degrees C was 0.21% (w/v). The amount of LAE bound per unit amount of pectin decreased with increasing pectin concentration (from 1.5 to 0.5 g/g for 0.05 to 0.5 wt % pectin) and with increasing temperature (from 1.7 to 1.3 g/g for 15 to 40 degrees C). The binding contribution to the LAE-pectin interaction was exothermic and was attributed to electrostatic attraction between the cationic surfactant and anionic biopolymer. This study demonstrates that lauric arginate can form either soluble or insoluble complexes with anionic biopolymers depending on the composition of the system.
Authors:
D Asker; J Weiss; D J McClements
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Langmuir : the ACS journal of surfaces and colloids     Volume:  25     ISSN:  0743-7463     ISO Abbreviation:  Langmuir     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-31     Completed Date:  2009-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9882736     Medline TA:  Langmuir     Country:  United States    
Other Details:
Languages:  eng     Pagination:  116-22     Citation Subset:  IM    
Affiliation:
Department of Food Science, University of Massachusetts, Amherst, Massachusetts 01003, USA.
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MeSH Terms
Descriptor/Qualifier:
Biopolymers / chemistry*
Calorimetry / methods*
Cations
Electrophoresis / methods*
Light
Pectins / chemistry*
Scattering, Radiation
Surface-Active Agents / chemistry*
Chemical
Reg. No./Substance:
0/Biopolymers; 0/Cations; 0/Pectins; 0/Surface-Active Agents; 9000-69-5/pectin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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