| Analysis of the genetic polymorphism of coagulation factor XIIIB (FXIIIB) by isoelectric focusing. | |
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MedLine Citation:
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PMID: 3234386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The genetic variants of the coagulation factor XIIIB (FXIIIB) were analyzed by isoelectric focusing, carried out in agarose gels and followed by immunofixation. The FXIIIB phenotypes were visualized by a combined staining procedure with Coomassie Brilliant Blue R-250 and silver nitrate. Improved resolution was accomplished in polyacrylamide gels by hybrid isoelectric focusing in immobilized pH gradients supplemented with carrier ampholytes. We examined a total of 1,604 unrelated, healthy individuals from Southern Germany. The frequencies for the FXIIIB alleles were B*1 = 0.7581, B*2 = 0.0843, B*3 = 0.1568 and B*4 = 0.0019. The theoretical exclusion rate for disputed paternity is 22.35%. |
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Authors:
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H J Leifheit; H Cleve |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Electrophoresis Volume: 9 ISSN: 0173-0835 ISO Abbreviation: Electrophoresis Publication Date: 1988 Aug |
Date Detail:
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Created Date: 1989-05-10 Completed Date: 1989-05-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8204476 Medline TA: Electrophoresis Country: GERMANY, EAST |
Other Details:
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Languages: eng Pagination: 426-9 Citation Subset: IM |
Affiliation:
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Blood Transfusion Service, Bavarian Red Cross, Munich, Federal Republic of Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ampholyte Mixtures Factor XIII / analysis, genetics* Humans Isoelectric Focusing Phenotype Polymorphism, Genetic* |
| Chemical | |
Reg. No./Substance:
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0/Ampholyte Mixtures; 9013-56-3/Factor XIII; 97089-56-0/factor XIIIb |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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