Document Detail

Analysis of genetic diversity and the determination of relationships among western Mediterranean horse breeds using microsatellite markers.
MedLine Citation:
PMID:  16965404     Owner:  NLM     Status:  MEDLINE    
The distribution of genetic diversity and the genetic relationships among western Mediterranean horse breeds were investigated using microsatellite markers. The examined sample included seven Spanish and three Italian local horse breeds and populations, plus a Spanish Thoroughbred outgroup. The total number of animals examined was 682 (on average 62 animals per breed; range 20-122). The microsatellite marker set analysed provided 128 alleles (10.7 alleles per locus). Within-breed genetic diversity was always high (>0.70), with breeds contributing about 8% of the total genetic variability. The mean molecular coancestry of the entire population examined was 0.205, Losino being the breed that contributed most. In addition to Nei's standard and Reynolds' genetic distances, pair-wise kinship distance and molecular coancestry were estimated. Remarkably similar breed rankings were obtained with all methods. Clustering analysis provided an accurate representation of the current genetic relationships among the breeds. Determining coancestry is useful for analysing genetic diversity distribution between and within breeds and provides a good framework for jointly analysing molecular markers and pedigree information. An integrated analysis was undertaken to obtain information on the population dynamics in western Mediterranean native horse populations, and to better determine conservation priorities.
D Marletta; I Tupac-Yupanqui; S Bordonaro; D García; A M Guastella; A Criscione; J Cañón; S Dunner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of animal breeding and genetics = Zeitschrift für Tierzüchtung und Züchtungsbiologie     Volume:  123     ISSN:  0931-2668     ISO Abbreviation:  J. Anim. Breed. Genet.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-12     Completed Date:  2006-12-11     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100955807     Medline TA:  J Anim Breed Genet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  315-25     Citation Subset:  IM    
DACPA, Sez. di Scienze delle Produzioni Animali, Facoltà di Agraria, Università degli studi di Catania, Catania, Italy.
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MeSH Terms
Cluster Analysis
Genetic Variation*
Horses / classification,  genetics*
Microsatellite Repeats*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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