| Analysis of fossa ovalis membrane velocities by transesophageal Doppler tissue echocardiography: a novel approach to functional assessment of patent foramen ovale. | |
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MedLine Citation:
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PMID: 15502790 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Recent studies have suggested that a higher mobility of the fossa ovalis membrane (FOM) may be associated with an increased risk for stroke in patients with patent foramen ovale (PFO). The current study analyzed whether Doppler tissue echocardiography is useful for quantitation of FOM motion velocities. METHODS: FOM dynamics were prospectively studied in 107 consecutive patients (average age 50.7 +/- 15.3 years, 48 men) with in sinus rhythm who underwent transesophageal echocardiography for various indications. With pulsed wave Doppler tissue echocardiography interrogation, a characteristic quadrophasic signal was recorded in all patients, consisting of a positive wave toward the left atrium (A-wave) at late diastole, followed by a negative wave (B-wave) toward the right atrium, a pronounced, again positive wave during midsystole (C-wave), and a final negative wave (D-wave). RESULTS: Peak velocities of A-wave, B-wave, C-wave, and D-wave were 0.08 +/- 0.02 m/s, 0.11 +/- 0.05 m/s, 0.17 +/- 0.07 m/s, and 0.14 +/- 0.06 m/s, respectively. In 21 of 107 (19.6%) patients, PFO was detected. Patients with PFO had significantly higher C-wave and D-wave peak velocities compared with the 86 patients without PFO (0.23 +/- 0.10 m/s vs 0.15 +/- 0.05 m/s, P < .001 and 0.16 +/- 0.07 m/s vs 0.12 +/- 0.06 m/s, P = .04, respectively). CONCLUSIONS: Assessment of FOM dynamics using Doppler tissue echocardiography is feasible. It allows definition of a characteristic quadrophasic FOM motion pattern, thereby providing new insights into the physiology of FOM mobility. Patients with PFO were found to have increased FOM mobility compared with patients without PFO. |
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Authors:
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Holger Eggebrecht; Christoph K Naber; Christiane Plato; Raimund Erbel; Thomas Bartel |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 17 ISSN: 0894-7317 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2004 Nov |
Date Detail:
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Created Date: 2004-10-25 Completed Date: 2005-02-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 1161-6 Citation Subset: IM |
Affiliation:
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West German Heart Center, Department of Cardiology, University of Duisburg-Essen, Essen, Germany. holger.eggebrecht@uni-essen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Chi-Square Distribution Contrast Media Echocardiography, Doppler, Pulsed Echocardiography, Transesophageal* Female Heart Septal Defects, Atrial / physiopathology*, ultrasonography* Humans Male Middle Aged Prospective Studies Sensitivity and Specificity Statistics, Nonparametric |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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