Document Detail


Analysis of the fatty acid composition of erythrocyte phospholipids by a base catalysed transesterification method--prevention of formation of dimethylacetals.
MedLine Citation:
PMID:  3349633     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A sensitive method for the analysis of the fatty acid composition of erythrocyte phospholipids with capillary column GLC is described. Under the assay conditions (base catalysed transesterification with sodium methoxide), only the fatty acids of the phospholipids are converted to their methylesters. The alkenyl ether chains of the plasmalogens are not transmethylated. This eliminates the need for thin layer chromatography for the separation of dimethylacetals and esterified fatty acids. The method is suitable for the measurement of the fatty acid patterns of erythrocyte phospholipids in small blood samples.
Authors:
M D Laryea; P Cieslicki; E Diekmann; U Wendel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  171     ISSN:  0009-8981     ISO Abbreviation:  Clin. Chim. Acta     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-05-05     Completed Date:  1988-05-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  11-8     Citation Subset:  IM    
Affiliation:
Universitäts-Kinderklinik Düsseldorf, Abteilung für allgemeine Pädiatrie, Stoffwechselerkrankungen, FRG.
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MeSH Terms
Descriptor/Qualifier:
Acetals
Catalysis
Chromatography, Gas
Erythrocytes / analysis*
Esterification
Fatty Acids / blood*
Humans
Hydrogen-Ion Concentration
Phospholipids / blood*
Chemical
Reg. No./Substance:
0/Acetals; 0/Fatty Acids; 0/Phospholipids

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