Document Detail

Analysis of factors influencing Dysphagia severity following treatment of head and neck cancer.
MedLine Citation:
PMID:  19661348     Owner:  NLM     Status:  MEDLINE    
The aim was to assess the influence of treatment, tumor stages and sites on the severity of dysphagia following treatment. Sequential modified barium swallow (MBS) examinations were performed in patients who complained of chronic dysphagia following treatment of their head and neck cancer. Patients were selected if they were cancer free at their last MBS and had 2 or more MBS studies. Dysphagia severity was graded on a scale of 1 to 7. Dysphagia grade was compared between the first and last MBS to assess its evolution. Between 1996 and 2005, 63 patients with chronic dysphagia underwent MBS to assess dysphagia severity for nutritional support. Twenty-one patients (33%) had improvement of their dysphagia. Two of these patients (3%) achieved normalization of the swallowing. Twenty-five patients (40%) had no change of the dysphagia severity. Dysphagia grade increased in 17 patients (27%). Analysis of patient characteristics did not show any significant difference between these three groups of patients. MBS is a useful tool to monitor dysphagia severity and to identify aspiration risk. Stages of disease and treatment modality do not seem to impact on the course of dysphagia.
Nam P Nguyen; Cheryl Frank; Candace C Moltz; Ulf Karlsson; Phuc D Nguyen; Harold Wc Ward; Paul Vos; Herbert J Smith; Shawn Huang; Ly M Nguyen; Claire Lemanski; Adir Ludin; Sabah Sallah
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anticancer research     Volume:  29     ISSN:  1791-7530     ISO Abbreviation:  Anticancer Res.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-08-07     Completed Date:  2009-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  3299-304     Citation Subset:  IM    
Radiation Oncology Department, University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724-5081, USA.
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MeSH Terms
Antineoplastic Agents / adverse effects*
Barium Sulfate
Carcinoma, Squamous Cell / complications*,  therapy
Combined Modality Therapy
Deglutition Disorders / etiology*
Head and Neck Neoplasms / complications*,  therapy
Middle Aged
Neoplasm Recurrence, Local / pathology,  therapy*
Retrospective Studies
Survival Rate
Treatment Outcome
Reg. No./Substance:
0/Antineoplastic Agents; 7727-43-7/Barium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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