| Analysis of the electrical excitation of CNS neurons. | |
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MedLine Citation:
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PMID: 9609941 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The artificial excitation process of neurons of the central nervous system depends on the applied extracellular field, on the geometry of the neuron and on the electrical properties of the neural subunits. Results of computer simulations are based on a compartment model of the neuron and its equivalent electrical network. Furthermore, a theory is presented which generalizes the activating function concept known from peripheral nerve stimulation. The theory predicts the influence of electrical and geometrical parameters on the excitation threshold. Generally, the myelinated axon is the part of a neuron which is most excitable to a given applied field. An example demonstrates that for a target neuron the quotient (anodic threshold current)/(cathodic threshold current) essentially depends on the position and orientation of the neuron relative to the electrode. |
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Authors:
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F Rattay |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: IEEE transactions on bio-medical engineering Volume: 45 ISSN: 0018-9294 ISO Abbreviation: IEEE Trans Biomed Eng Publication Date: 1998 Jun |
Date Detail:
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Created Date: 1998-06-16 Completed Date: 1998-06-16 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0012737 Medline TA: IEEE Trans Biomed Eng Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 766-72 Citation Subset: IM |
Affiliation:
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Technical University Vienna, Austria. frattay@email.tuwien.ac.at |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Axons
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physiology Computer Simulation* Electric Stimulation* Electrodes Electromagnetic Fields Models, Neurological* Neural Conduction / physiology* Neurons / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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