| [Analysis on detection of enterovirus nucleotides in feces samples of hand-foot-mouth disease patients after recovery]. | |
| | |
MedLine Citation:
|
PMID: 22336339 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
OBJECTIVE: To explore the duration of enterovirus (EV) nucleotides positive in feces samples of hand-foot-mouth disease (HFMD) patients after recovery. METHODS: A consecutive 6-week follow up were carried out towards 49 cases of laboratory-diagnosed HFMD patients. A total of 5 - 8 g feces sample was collected from each patient once a week. The common EV nucleotides of HFMD were detected by RT-PCR method and analyzed by Kaplan-Meier Survival Analysis Method. RESULTS: The subtypes of the 49 HFMD patients included 16 enterovirus 71 (EV71), 15 coxasckievirus A16 (CoxA16) and 18 EV; a six-week follow up was carried out among all of them. In the first week, one EV71 patient and two EV patients were lost; in the fourth week, one CoxA16 were lost; and in the fifth week, one EV71 patient was lost. During the consecutive 6-week follow-up, the positive rates of EV nucleotides among EV71 patients were 81.3%, 60.9%, 47.4%, 33.9%, 27.1% and 18.1% separately; and the positive rates in CoxA16 group were 93.3%, 73.3%, 53.3%, 33.3%, 16.7% and 8.3% respectively. In EV group, the positive rates of EV nucleotides were 44.4% and 7.4% in the first two weeks and then turned to negative in the next 4 weeks. There was significant statistical difference in positive rates of EV nucleotides among different patients (χ(2) = 11.78, P = 0.001); however, each group of HFMD patients showed a declined trend with the extension of time. CONCLUSION: The duration of EV nucleotides positive in feces samples of HFMD patients lasted for a long period since their recovery; and the positive results in EV71 and CoxA16 patients might last for 6 weeks. |
| | |
Authors:
|
Yi-Lin He; Xiang Zhang; Jie Zha; Wen-Jun Dai; Feng Luo; Tao Shen |
Publication Detail:
|
Type: English Abstract; Journal Article |
Journal Detail:
|
Title: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] Volume: 45 ISSN: 0253-9624 ISO Abbreviation: Zhonghua Yu Fang Yi Xue Za Zhi Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2012-02-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7904962 Medline TA: Zhonghua Yu Fang Yi Xue Za Zhi Country: China |
Other Details:
|
Languages: chi Pagination: 1073-6 Citation Subset: IM |
Affiliation:
|
Department of Acute Infectious Disease Control and Prevention, Center for Disease Prevention and Control of Taizhou, Taizhou 225300, China. Email: heyilin001@126.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [Investigation on levels of polybrominated diphenyl ethers in retail fish and egg products in Shenzh...
Next Document: [The coverage rate and obstructive factors of influenza vaccine inoculation among residents aged abo...