Document Detail


Analysis of a cone snail's killer cocktail--the milked venom of Conus geographus.
MedLine Citation:
PMID:  22884604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
"Snails can kill" is a statement that receives much disbelief. Yet the venom from Conus geographus, as delivered by a disposable hypodermic-like needle, has indeed killed many unsuspecting human victims. Our understanding of their milked venom the essence of these fatalities, is in itself non-existent. Here, we present the molecular mass analysis of the milked venom of C. geographus, providing the first insight into the composition of its deadly cocktail.
Authors:
Jon-Paul Bingham; Margaret R Baker; Joycelyn B Chun
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2012-08-04
Journal Detail:
Title:  Toxicon : official journal of the International Society on Toxinology     Volume:  60     ISSN:  1879-3150     ISO Abbreviation:  Toxicon     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-09-17     Completed Date:  2013-02-08     Revised Date:  2013-11-06    
Medline Journal Info:
Nlm Unique ID:  1307333     Medline TA:  Toxicon     Country:  England    
Other Details:
Languages:  eng     Pagination:  1166-70     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Molecular Biosciences and Bioengineering, College of Tropical Agriculture and Human Resources, University of Hawaii, Honolulu, HI 96822, USA. jbingham@hawaii.edu
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Animals
Chromatography, High Pressure Liquid
Conus Snail / chemistry*
Molecular Sequence Data
Molecular Weight
Mollusk Venoms / analysis*
Species Specificity
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Grant Support
ID/Acronym/Agency:
5 G12 RR003061-26/RR/NCRR NIH HHS; 8 G12 MD007601-26/MD/NIMHD NIH HHS; G12 MD007601/MD/NIMHD NIH HHS; G12 RR003061/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Mollusk Venoms
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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