Document Detail


Analysis of clinical, radiological and laboratory variables in psoriatic arthritis with 25 Japanese patients.
MedLine Citation:
PMID:  20629831     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Psoriatic arthritis (PsA) has many clinical and radiological manifestations but lacks a specific laboratory marker. The aim of the present study was to identify noteworthy features in PsA patients on routine clinical examinations. The subjects were 25 PsA patients who were classified based on the Classification of Psoriatic Arthritis (CASPAR) criteria. The clinical and radiological findings and laboratory parameters were analyzed by retrospective chart review. On clinical examination, dactylitis was present in 13 (52%) of 25 patients, swollen and/or tender Achilles tendons were present in nine (36%), and sacroiliitis was present in eight (32%). Of the radiological features, juxta-articular new bone formation (JANF) was seen in 12 (48%), extra-articular new bone formation was seen in nine (36%) and sacroiliitis was seen in six (24%). Dactylitis and JANF had the highest prevalence rates. The Psoriasis Area and Severity Index score, swollen and/or tender joint count, erythrocyte sedimentation rate, C-reactive protein, and matrix metalloproteinase-3 were higher in patients with sacroiliitis than in those without sacroiliitis (P < 0.05). Dactylitis, JANF and sacroiliitis may be noteworthy manifestations in Japanese patients with PsA.
Authors:
Hideki Maejima; Tomonori Taniguchi; Akira Watarai; Ryouichi Aki; Kensei Katsuoka
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  37     ISSN:  1346-8138     ISO Abbreviation:  J. Dermatol.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-15     Completed Date:  2010-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  647-56     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan. hm4765@yahoo.co.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Arthritis, Psoriatic / classification*,  diagnosis*,  radiography
Asian Continental Ancestry Group
Blood Sedimentation
C-Reactive Protein / analysis
Female
Finger Joint / radiography
Humans
Male
Matrix Metalloproteinase 3 / blood
Middle Aged
Osteogenesis
Retrospective Studies
Severity of Illness Index
Tendinopathy / classification,  diagnosis,  radiography
Chemical
Reg. No./Substance:
9007-41-4/C-Reactive Protein; EC 3.4.24.17/Matrix Metalloproteinase 3

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