Document Detail

Analysis of children with peripheral lymphadenopathy.
MedLine Citation:
PMID:  16893860     Owner:  NLM     Status:  MEDLINE    
In this study, the clinical and laboratory features of children with lymphadenopathy were evaluated. Over a 3-year period, 126 patients were referred to the clinic for lymphadenopathy. Twenty-eight of cases have diseases mimicking lymphadenopathy; 98 (mean age: 86+/-55 months) have lymphadenopathy. Localized, limited, and generalized involvement was found in 52%, 30%, and 18% of patients. The most common localization was the head and neck region. The causes of lymphadenopathy were benign diseases in 75 patients. Sixty percent were reactive lymphadenopathy, 39% were lymphadenitis. Lymphadenitis was more frequently localized and bigger than 3 cm compared with reactive adenopathy (p=.02, p=.004). Twenty-three patients have malignant diseases whose mean age was higher than others (p=.002). The enlargement of supraclavicular nodes was more likely due to malignant disease (p=.001). The risk of malignant disease was higher in patients who had generalized lymphadenopathy, lymph nodes bigger than 3 cm, hepatosplenomegaly, and high lactate dehydrogenase levels. In conclusion, this study pointed out the important clues for the differential diagnosis, which were present in the history, physical, and laboratory findings.
Nilgun Yaris; Murat Cakir; Emin Sözen; Umit Cobanoglu
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  45     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-08-08     Completed Date:  2006-11-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  544-9     Citation Subset:  AIM; IM    
Department of Pediatric Oncology and Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey.
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MeSH Terms
Child, Preschool
Lymph Nodes / pathology
Lymphadenitis / pathology
Lymphatic Diseases / diagnosis*,  pathology
Lymphatic Vessel Tumors / diagnosis,  pathology
Lymphoma / diagnosis,  pathology

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