| Analysis of children with peripheral lymphadenopathy. | |
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MedLine Citation:
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PMID: 16893860 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this study, the clinical and laboratory features of children with lymphadenopathy were evaluated. Over a 3-year period, 126 patients were referred to the clinic for lymphadenopathy. Twenty-eight of cases have diseases mimicking lymphadenopathy; 98 (mean age: 86+/-55 months) have lymphadenopathy. Localized, limited, and generalized involvement was found in 52%, 30%, and 18% of patients. The most common localization was the head and neck region. The causes of lymphadenopathy were benign diseases in 75 patients. Sixty percent were reactive lymphadenopathy, 39% were lymphadenitis. Lymphadenitis was more frequently localized and bigger than 3 cm compared with reactive adenopathy (p=.02, p=.004). Twenty-three patients have malignant diseases whose mean age was higher than others (p=.002). The enlargement of supraclavicular nodes was more likely due to malignant disease (p=.001). The risk of malignant disease was higher in patients who had generalized lymphadenopathy, lymph nodes bigger than 3 cm, hepatosplenomegaly, and high lactate dehydrogenase levels. In conclusion, this study pointed out the important clues for the differential diagnosis, which were present in the history, physical, and laboratory findings. |
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Authors:
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Nilgun Yaris; Murat Cakir; Emin Sözen; Umit Cobanoglu |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical pediatrics Volume: 45 ISSN: 0009-9228 ISO Abbreviation: Clin Pediatr (Phila) Publication Date: 2006 Jul |
Date Detail:
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Created Date: 2006-08-08 Completed Date: 2006-11-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372606 Medline TA: Clin Pediatr (Phila) Country: United States |
Other Details:
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Languages: eng Pagination: 544-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatric Oncology and Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Child, Preschool Female Humans Infant Lymph Nodes / pathology Lymphadenitis / pathology Lymphatic Diseases / diagnosis*, pathology Lymphatic Vessel Tumors / diagnosis, pathology Lymphoma / diagnosis, pathology Male |
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