| Analysis of cellular populations in peritoneal effluents of children on CAPD. | |
| | |
MedLine Citation:
|
PMID: 2582649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The characterization of cellular populations in peritoneal effluents (PE) of CAPD patients has been the subject of few studies. In order to establish a possible correlation between PE cells and clinical parameters, we studied the immunocompetent cells that are found in uncomplicated patients. In this study we used cytofluorimetric analysis to characterize phenotypically immunocompetent PE cells. We studied 17 children with a mean age of 8.7 +/- 5.3 years, who had been on CAPD for a mean duration of 16 months. The patients never suffered from peritonitis. The effluents were collected after overnight dialysis and centrifuged to concentrate cells. Surface phenotype of PE cells was tested with a panel of monoclonal antibodies. The analysis of 40 PE samples showed that the various cell types were present with different frequencies, suggesting that a dominant phenotype cannot be defined. The ratio between M3 positive cells (monocytic-macrophagic lineage) and T3 positive cells (T lymphocytes) showed a tendency to decrease after initiation of CAPD. T4/T8 ratio in all samples did not differ from that of peripheral lymphocytes. A high frequency of activated T cells (41% +/- 13), defined by the presence of DR antigens on T3+ M3- cells, was seen in PE and confirmed by the high frequency of T cells expressing the IL-2 receptor. |
| | |
Authors:
|
M T Valle; M L Degl'Innocenti; P Giordano; A Kunkl; M T Costantini; F Perfumo; F Manca; R Gusmano |
Related Documents
:
|
6601359 - Non-hodgkin's lymphoma in northwestern kyushu island of japan. clinicopathological stud... 15036989 - The use of cytological examination of vaginal smears (cevs) in the selection of rabbits... 22282019 - Mass spectrometric analysis identifies a cortactin-rcc2/td60 interaction in mitotic cells. 364909 - Diagnostic cytologic sample profiles in patients with bladder cancer using ticas system. 22552829 - Selective radiosensitization of human cervical cancer cells and normal cells by artemis... 22306999 - Transient overexpression of cyclin d2/cdk4/glp1 genes induces proliferation and differe... 22415709 - The over-expression of cell migratory genes in alveolar rhabdomyosarcoma could contribu... 10739679 - An established light ear mutant (c57bl/6j-pdeb(rd1) le) mouse cell line exhibits a bloc... 18606719 - Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cell... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical nephrology Volume: 32 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 1989 Nov |
Date Detail:
|
Created Date: 1989-12-28 Completed Date: 1989-12-28 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: GERMANY, WEST |
Other Details:
|
Languages: eng Pagination: 235-8 Citation Subset: IM |
Affiliation:
|
Immunology Unit, S. Martino Hospital, XIII USL, Genoa, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Child Child, Preschool Flow Cytometry / methods Humans Kidney Failure, Chronic / therapy* Macrophages / cytology Monocytes / cytology Peritoneal Cavity / pathology* Peritoneal Dialysis, Continuous Ambulatory* T-Lymphocytes / cytology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Renal functional reserve in patients with a reduced number of functioning glomeruli.
Next Document: Campylobacter pylori: prevalence and significance in patients with chronic renal failure.