Document Detail

Analysis of cell types in the corpus luteum of the sheep.
MedLine Citation:
PMID:  2810229     Owner:  NLM     Status:  MEDLINE    
The parenchyma of the corpus luteum of the ewe consists of two distinct steroidogenic cell types: small luteal cells and large luteal cells. Although both cell types produce and secrete progesterone, they differ with respect to morphological and biochemical characteristics. During the oestrous cycle, and continuing into pregnancy, the cellular composition of the corpus luteum is altered. As the oestrous cycle progresses small luteal cells increase in number but not size whereas large luteal cells remain constant in number but increase in size. Changes in the cellular composition of the ovine corpus luteum appear to be regulated by LH. Moreover, small luteal cells obtained from pregnant ewes were larger and lacked responsiveness to LH compared to those from non-pregnant animals. The basis of this loss of responsiveness is not clear as there is no concomitant loss of receptors for LH. The corpus luteum is a dynamic gland which changes in cellular composition and hormonal responsiveness with alterations in the reproductive state of the animal.
C E Farin; H R Sawyer; G D Niswender
Related Documents :
3040379 - Specific receptor-mediated stimulation of progesterone secretion and cgmp accumulation ...
6747949 - Steroid production by isolated theca and granulosa cells after initiation of atresia in...
8365349 - Solitary and synaptonemal complex-associated recombination nodules in pro-nurse cells d...
1036339 - Post ovulatory follicles of the domestic duck.
2480959 - Cyclic amp-dependent and -independent regulation of cholesterol side chain cleavage cyt...
2362449 - Potency and selectivity of the aromatase inhibitor r 76,713. a study in human ovarian, ...
2547049 - Undifferentiated columnar cells in colorectal adenomas and familial adenomatous polyposis.
20717959 - Asymmetrical cell division and differentiation are not dependent upon stratification in...
17958419 - Harnessing functional plasticity of enzymes: a fluorogenic probe for imaging 17beta-hsd...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of reproduction and fertility. Supplement     Volume:  37     ISSN:  0449-3087     ISO Abbreviation:  J. Reprod. Fertil. Suppl.     Publication Date:  1989  
Date Detail:
Created Date:  1989-12-13     Completed Date:  1989-12-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0225652     Medline TA:  J Reprod Fertil Suppl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  181-7     Citation Subset:  IM    
Department of Physiology, Colorado State University, Fort Collins 80523.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Corpus Luteum / cytology*,  physiology
Luteinizing Hormone / physiology
Pregnancy, Animal / physiology*
Sheep / anatomy & histology*
Grant Support
Reg. No./Substance:
9002-67-9/Luteinizing Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Low molecular weight lipid-soluble luteotrophic factor(s) produced by conceptuses in cows.
Next Document:  In-vivo effect of prostaglandin F-2 alpha treatment on secretory granules in the corpus luteum of th...