Document Detail

Analysis by MRI of residual tumor after radiofrequency ablation for early stage breast cancer.
MedLine Citation:
PMID:  22358027     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: The objective of our study was to evaluate the effectiveness of MRI in the detection of possible residual lesions after radiofrequency ablation (RFA) in the treatment of breast cancer.
SUBJECTS AND METHODS: We prospectively evaluated 14 patients who had undergone ultrasound-guided core biopsies diagnostic of invasive ductal carcinoma (IDC; range of diameters, 1.0-3.0 cm) and then ultrasound-guided percutaneous RFA with sentinel node biopsy as the primary treatment. Breast MRI was performed 1 week before RFA to evaluate tumor extension and again 3 weeks after RFA to verify the presence of possible residual lesions. Conventional surgical resection of the tumors was performed 1 week after RFA. The MRI findings were compared with histopathologic analyses to confirm the presence or absence of residual tumor.
RESULTS: There was no residual enhancement in seven lesions on the postablation breast MRI scans. These findings were confirmed by negative histopathologic findings in the surgical specimens. The MRI scans of five patients showed small areas of irregular enhancement that corresponded to residual lesions. In the two remaining patients, we observed enhancement of almost the entire lesion, indicating that RFA had failed.
CONCLUSION: Breast MRI is effective in detecting residual lesions after RFA in patients with IDC.
Vanessa Sales Vilar; Suzan Menasce Goldman; Marcos Desidério Ricci; Katia Pincerato; Helio Oliveira; Thiago Giansante Abud; Sergio Ajzen; Edmund Chada Baracat; Jacob Szejnfeld
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  198     ISSN:  1546-3141     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  W285-91     Citation Subset:  AIM; IM    
Department of Diagnostic Imaging, Federal University of Sao Paulo, Rua Napoleão de Barros, 800, Vila Clementino, Sao Paulo 04024-000, Brazil.
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