Document Detail


Analysis of bone formation after sinus augmentation using β-tricalcium phosphate.
MedLine Citation:
PMID:  22616219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Implant placement in the edentulous maxilla often represents a clinical challenge due to insufficient bone height after crestal bone resorption and maxillary sinus pneumatization. Several graft materials have been evaluated for augmenting the maxillary sinus to compensate for the lost vertical dimension. Allografts are readily available without the risk of disease transmission and the need for a second site surgery. The aim of this case series was to systematically evaluate the development and maturation of augmented bone in the maxillary sinus using beta-tricalcium phosphate. In 21 to 40 weeks post-sinus elevation, bone biopsies were taken and implants placed simultaneously. All specimens were demineralized and subjected to staining procedures (ie, Hematoxylin and Eosin [H&E], Goldner's staining, and tartrate-resistant acid phosphatase [TRAP]). Total bone increased over time, whereas the amount of graft material diminished. A lack of inflammatory reaction was noticed with the use of this graft material. In addition, TRAP staining revealed the presence of osteoclasts surrounding the remaining particles. During a 12-month follow-up, no implant failure or complications were observed.
Authors:
Ulrike Schulze-Späte; Thomas Dietrich; Rayyan A Kayal; Hatice Hasturk; Justine Dobeck; Ziedonis Skobe; Serge Dibart
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)     Volume:  33     ISSN:  1548-8578     ISO Abbreviation:  Compend Contin Educ Dent     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-23     Completed Date:  2012-08-15     Revised Date:  2013-05-14    
Medline Journal Info:
Nlm Unique ID:  9600713     Medline TA:  Compend Contin Educ Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  364-8     Citation Subset:  D    
Affiliation:
Division of Periodontics, Section of Oral and Diagnostic Sciences, College of Dental Medicine, Columbia University, New York, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Absorbable Implants
Acid Phosphatase / analysis
Adult
Aged
Biological Markers / analysis
Biopsy
Bone Substitutes / therapeutic use*
Calcium Phosphates / therapeutic use*
Collagen
Coloring Agents / diagnostic use
Dental Implantation, Endosseous / methods
Female
Follow-Up Studies
Humans
Isoenzymes / analysis
Male
Maxilla / pathology,  surgery
Maxillary Sinus / pathology,  surgery
Membranes, Artificial
Middle Aged
Osseointegration / physiology
Osteoclasts / pathology
Osteogenesis / physiology*
Sinus Floor Augmentation / methods*
Grant Support
ID/Acronym/Agency:
L30 DE018609/DE/NIDCR NIH HHS; M01 RR00533/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Bone Substitutes; 0/Calcium Phosphates; 0/Coloring Agents; 0/Isoenzymes; 0/Membranes, Artificial; 0/beta-tricalcium phosphate; 9007-34-5/Collagen; EC 3.1.3.-/tartrate-resistant acid phosphatase; EC 3.1.3.2/Acid Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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