Document Detail


Analysis of aryl hydrocarbon receptor ligands in kraft mill effluents by a combination of yeast bioassays and CG-MS chemical determinations.
MedLine Citation:
PMID:  23043335     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aryl Hydrocarbon Receptor (AhR) ligands also known as dioxin-like compounds, constitute a substantial part of the total toxicity from many pollution sources, including pulp mill effluents. The aim of this article was to evaluate dioxin-like activity in different kraft mill effluents by a combination of yeast bioassays and gas chromatography-mass spectrometry (GC-MS) chemical analysis. The study includes kraft mill effluents from three sources of raw material: Pinus radiata, Eucalyptus globulus and a combination of both (50% each). The Recombinant Yeast Assay (RYA) showed an effective concentration of AhR ligands more than 30-fold higher in Eucalyptus globulus than in Pinus radiata effluents. Our results suggest that specific ligands, rather than the total amount of extractive material, determined the observed activity. Analysis of extract composition by GC-MS indicated that moderately hydrophobic aromatic compounds were likely responsible for the observed dioxin-like activity. In particular, benzaldehyde derivatives appeared as candidates for eliciting the observed dioxin-like activity in pulp mill effluents, giving their structural properties and their high concentration in AhR ligand-rich samples.
Authors:
Soledad Chamorro; Elizabeth Monsalvez; Benjamín Piña; Alba Olivares; Víctor Hernández; José Becerra; Gladys Vidal
Related Documents :
23363025 - Determination of light-medium-heavy polycyclic aromatic hydrocarbons in vegetable oils ...
23604835 - Hplc of trichothecenes - separation of neosolaniol, nt-1 toxin, and nt-2 toxin.
24424965 - Lc-qtof-ms as a superior strategy to immunoassay for the comprehensive analysis of synt...
23787185 - A pair of sulfonated diarylheptanoid epimers from kaempferia galanga.
17161665 - High performance liquid chromatography-electrospray ionization mass spectrometric deter...
6468445 - Seven years of experience with selective screening for organic acidurias.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering     Volume:  48     ISSN:  1532-4117     ISO Abbreviation:  J Environ Sci Health A Tox Hazard Subst Environ Eng     Publication Date:  2013  
Date Detail:
Created Date:  2012-10-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9812551     Medline TA:  J Environ Sci Health A Tox Hazard Subst Environ Eng     Country:  England    
Other Details:
Languages:  eng     Pagination:  145-51     Citation Subset:  IM    
Affiliation:
a Environmental Science Center EULA-Chile , University of Concepción , Concepción , Chile.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Polyhalogenated aromatic hydrocarbons in surface sediments from Three Gorges Reservoir.
Next Document:  1-Hydroxypyrene as a biomarker for assessing the effects of exposure to polycyclic aromatic hydrocar...