Document Detail

Analysis of acid-base properties of riboflavin calculated via semi-empirical methods.
MedLine Citation:
PMID:  18536174     Owner:  NLM     Status:  MEDLINE    
A number of physicochemical parameters were calculated via semi-empirical methods AM1 and PM3 for the molecule of riboflavin at various protonation states. Their analysis made it possible to determine the acidicity of appropriate groups of this compound. The sequence of protons dissociation and accepting by the neutral molecule of riboflavin was determined. This methodology may be used to study acid-base properties of other biologically active compounds.
Elzbieta Brzezińska; Cecylia Mielczarek; Wojciech Pajak
Related Documents :
19879184 - Spectrophotometric determination of [2-(2,6-dichloro-phenylamino)-phenyl]-acetic acid i...
6833784 - Quantitative analysis of eumelanin and pheomelanin in hair and melanomas.
3240374 - A gas chromatographic mass spectrometric method for the analysis of trifluoroacetic aci...
17598024 - Spectrofluorimetric determination of tranexamic acid in hydrogel patch formulations by ...
15979124 - Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and...
2874954 - Comparative actions of quisqualate and n-methyl-d-aspartate, excitatory amino acid agon...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta poloniae pharmaceutica     Volume:  65     ISSN:  0001-6837     ISO Abbreviation:  Acta Pol Pharm     Publication Date:    2008 Jan-Feb
Date Detail:
Created Date:  2008-06-09     Completed Date:  2008-06-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985167R     Medline TA:  Acta Pol Pharm     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  59-63     Citation Subset:  IM    
Department of Analytical Chemistry, Faculty of Pharmacy, Medical University of Łódź, Poland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acid-Base Equilibrium*
Empirical Research
Models, Molecular
Riboflavin / chemistry*
Vitamin B Complex / chemistry*
Reg. No./Substance:
0/Protons; 12001-76-2/Vitamin B Complex; 83-88-5/Riboflavin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Application of selected topological indices to predict retention parameters of selected bile acids s...
Next Document:  Flow cytometry application for studies on adenosine A2A receptors expression.