Document Detail

Analysis of Z-score distribution for the quality control of fetal ultrasound measurements at 20-24 weeks.
MedLine Citation:
PMID:  16308899     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To develop and evaluate the feasibility of Z-score distribution-based quality assessment for fetal biometry at 20-24 gestational weeks. METHODS: Four sonographers measured fetal biparietal diameter, head circumference, abdominal circumference and femur length in unselected pregnancies undergoing routine sonography at 20-24 weeks in our center between June 2001 and January 2004. All measurements were transformed into Z-scores. Distributions of Z-scores were compared with the expected standard normal distribution based on mean, SD and the Kolmogorov-Smirnov test. Modelling was performed to assess the sensitivity, specificity and Youden's index (sensitivity + specificity - 1) of each sonographer, reflecting their ability to detect fetuses with abnormal biometry in our population. RESULTS: A total of 5241 ultrasound examinations were included. None of the Z-score distributions could be considered similar to the standard normal distribution: means of Z-scores ranged from -0.604 to 0.73 and the SD ranged from 0.726 to 0.896. Sensitivity and specificity ranged from 25.31% to 68.67% and 93.44% to 100%, respectively; Youden's index ranged from 0.25 to 0.69. CONCLUSION: Analysis of Z-score distribution can be used to assess the quality of fetal measurements. Several indices can be extracted from this analysis in order to improve quality assessment of fetal biometry measured by ultrasound.
L J Salomon; J P Bernard; Y Ville
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  26     ISSN:  0960-7692     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-01     Completed Date:  2006-02-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  750-4     Citation Subset:  IM    
Service de Gyn?cologie-Obst?trique, Centre Hospitalier Intercommunal de Poissy-St Germain, Poissy, France.
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MeSH Terms
Abdomen / anatomy & histology,  embryology,  ultrasonography
Anthropometry / methods
Cephalometry / methods,  standards
Feasibility Studies
Femur / anatomy & histology,  embryology,  ultrasonography
Fetus / anatomy & histology*
Gestational Age
Quality Assurance, Health Care
Reference Values
Ultrasonography, Prenatal / standards*

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