| Analysis of Y-graft blood flow and flow reserve in conditions of increased myocardial oxygen consumption. | |
| | |
MedLine Citation:
|
PMID: 15185888 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: It is not well established whether early following surgery the blood flow of arterial composite Y-grafts may efficiently meet the flow demand of the coronary system. The aim of this study was to evaluate whether early after surgery arterial composite Y-grafts may increase the blood flow in response to an increase in myocardial oxygen consumption (MVO2). METHODS: Twenty-seven patients who received complete arterial myocardial revascularization using the left internal thoracic artery (LITA) and the radial artery (RA) as composite Y-graft gave their consent to a pre-discharge coronary angiography and intravascular flow velocity measurements using a Doppler guidewire. Flow measurements were performed in the LITA main stem, the distal LITA and the RA, both at rest and during atrial pacing at 85% of the patient age-predicted maximum heart rate. The heart rate-systolic blood pressure product was considered as an indirect index of MVO2. Hyperemic flow was determined after injection of adenosine. The flow reserve was defined as the ratio of blood flow during maximal hyperemia (Qmax) to baseline flow (Qbasal). RESULTS: Atrial pacing significantly increased MVO2 (p < 0.000). None of the patients developed ischemic ST-segment modifications or complained of chest pain. Qbasal increased significantly in the LITA main stem (p = 0.001), distal LITA (p = 0.041) and RA (p = 0.004) while Qmax did not change significantly. As a consequence the flow reserve decreased in the LITA main stem (p = 0.002), distal LITA (p = 0.000) and RA (p = 0.000) but was not completely exhausted. CONCLUSIONS: Early after surgery arterial composite Y-grafts may significantly increase blood flow in response to conditions of increased MVO2 and maintain a normal myocardial oxygen supply-to-demand ratio. |
| | |
Authors:
|
Massimo Lemma; Andrea Mangini; Guido Gelpi; Andrea Innorta; Amedeo Spina; Carlo Antona |
Related Documents
:
|
16904678 - Importance of flow division on transition to turbulence within an arteriovenous graft. 15608438 - Intimal hyperplasia in mouse vein grafts is regulated by flow. 1567118 - Blood flow of the areola and breast skin flaps during reduction mammaplasty as measured... 19318918 - Hemodynamic performance study on small diameter helical grafts. 8534778 - Acute effects of indomethacin on cerebral hemodynamics and oxygenation. 12802488 - Red blood cell rheology in sepsis. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Italian heart journal : official journal of the Italian Federation of Cardiology Volume: 5 ISSN: 1129-471X ISO Abbreviation: Ital Heart J Publication Date: 2004 Apr |
Date Detail:
|
Created Date: 2004-06-09 Completed Date: 2004-10-07 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 100909716 Medline TA: Ital Heart J Country: Italy |
Other Details:
|
Languages: eng Pagination: 290-4 Citation Subset: IM |
Affiliation:
|
Division of Cardiovascular Surgery, L. Sacco Hospital, Milan, Italy. massimo.lemma@fastwebnet.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Anastomosis, Surgical Blood Flow Velocity Coronary Angiography Coronary Artery Bypass / methods* Coronary Artery Disease / diagnosis, physiopathology, surgery* Coronary Circulation Female Humans Male Mammary Arteries / physiopathology*, transplantation* Middle Aged Postoperative Period Radial Artery / physiopathology*, transplantation* Time Factors Ultrasonography, Interventional |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Survival after stentless and stented xenograft aortic valve replacement: a concurrent, case-match tr...
Next Document: Left atrial cardiac hemangioma: a report of two cases.