Document Detail

Analysis of the QRS complex for apnea-bradycardia characterization in preterm infants.
MedLine Citation:
PMID:  19963984     Owner:  NLM     Status:  MEDLINE    
This work presents an analysis of the information content of new features derived from the electrocardiogram (ECG) for the characterization of apnea-bradycardia events in preterm infants. Automatic beat detection and segmentation methods have been adapted to the ECG signals from preterm infants, through the application of two evolutionary algorithms. ECG data acquired from 32 preterm infants with persistent apnea-bradycardia have been used for quantitative evaluation. The adaptation procedure led to an improved sensitivity and positive predictive value, and a reduced jitter for the detection of the R-wave, QRS onset, QRS offset, and iso-electric level. Additionally, time series representing the RR interval, R-wave amplitude and QRS duration, were automatically extracted for periods at rest, before, during and after apnea-bradycardia episodes. Significant variations (p<0.05) were observed for all time-series when comparing the difference between values at rest versus values just before the bradycardia event, with the difference between values at rest versus values during the bradycardia event. These results reveal changes in the R-wave amplitude and QRS duration, appearing at the onset and termination of apnea-bradycardia episodes, which could be potentially useful for the early detection and characterization of these episodes.
M Altuve; G Carrault; J Cruz; A Beuchae; P Pladys; A Hernandez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2009     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-07     Completed Date:  2010-04-02     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  946-9     Citation Subset:  IM    
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MeSH Terms
Bradycardia / complications,  diagnosis*
Diagnosis, Computer-Assisted / methods*
Electrocardiography / methods*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / diagnosis*
Reproducibility of Results
Sensitivity and Specificity
Sleep Apnea Syndromes / complications,  diagnosis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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