Document Detail

Analysis of placental vascularization by means of 3D power doppler in women pregnant following oocyte donation.
MedLine Citation:
PMID:  20595707     Owner:  NLM     Status:  In-Process    
OBJECTIVE: To analyze the differences in placental perfusion in pregnancies following oocyte donation compared to spontaneous pregnancies. PARTICIPANTS AND METHODS: A total of 33 patients who became pregnant after oocyte donation are studied and compared to 42 spontaneously pregnant participants. A 3-dimensional Power Doppler is used to obtain 3 placental volumes. Of each volume, 3 portions are analyzed in the form of a spherical ''placental biopsy.'' Four vascularization rates are applied, using the virtual organ computer-aided analysis (VOCAL) method: grey index (GI), vascularization index (VI), flow index (FI), and vascularization-flow index (VFI). RESULTS: Vascular alterations are demonstrated, manifested by a lower IG and a significantly higher IV in the group of spontaneous pregnancies (GI P = .001; (VI) P = .039) and is almost statistically significant in comparison to the IVF (P = .051). CONCLUSIONS: Placental perfusion in pregnancies obtained following oocyte donation is deficient in comparison to spontaneous pregnancies.
F Sellers López; Domingo Orozco-Beltran; Vicente Gil-Guillen; J M Lozano; A Palacios; R Bernabeu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproductive sciences (Thousand Oaks, Calif.)     Volume:  17     ISSN:  1933-7205     ISO Abbreviation:  Reprod Sci     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101291249     Medline TA:  Reprod Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  754-9     Citation Subset:  IM    
Bernabeu Institute of Fertility and Gynecology, Alicante, Spain.
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