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Analysis of DNA sequence variation within marine species using Beta-coalescents.
MedLine Citation:
PMID:  23142015     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme reproductive behaviour, e.g. via Hedgecock's "reproduction sweepstakes". Besides the data analysis, in particular the inference of mutation rates and the estimation of the (real) time to the most recent common ancestor, we briefly address the question whether the genealogies might be adequately described by so-called Beta coalescents (as opposed to Kingman's coalescent), allowing multiple mergers of genealogies. The choice of the underlying coalescent model for the genealogy has drastic implications for the estimation of the above quantities, in particular the real-time embedding of the genealogy.
Authors:
Matthias Steinrücken; Matthias Birkner; Jochen Blath
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-6
Journal Detail:
Title:  Theoretical population biology     Volume:  -     ISSN:  1096-0325     ISO Abbreviation:  Theor Popul Biol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0256422     Medline TA:  Theor Popul Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Inc.
Affiliation:
Department of Statistics, University of California, 367 Evans Hall MC 3860, Berkeley, CA 94720-3860, USA. Electronic address: steinrue@stat.berkeley.edu.
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