Document Detail

Analyses of left ventricular myocardial deformation by speckle-tracking imaging during the acute phase of Kawasaki disease.
MedLine Citation:
PMID:  20405115     Owner:  NLM     Status:  MEDLINE    
This study aimed to investigate left ventricular myocardial deformation in children with Kawasaki disease during the acute phase of their illness. A total of 50 patients and 35 normal control subjects were assessed. Data were obtained from the patients during the acute and convalescent phases of Kawasaki disease. Analyses of myocardial deformation [strain (epsilon), strain rate (SR)] was performed using two-dimensional speckle-tracking imaging in three directions (longitudinal, circumferential, and radial) at the basal and mid levels of the left ventricular myocardium. Basal longitudinal epsilon (P < 0.001) and midlongitudinal epsilon (P < 0.0001) were lower during the acute phase of the disease than in the control subjects and associated with serum albumin level and left ventricular mass index (LVMI). Midlongitudinal SR (P < 0.0001) was lower during the acute phase of Kawasaki disease than in the control subjects and associated with LVMI. Decreased systolic SR was not detected in any direction. In conclusion, left ventricular longitudinal systolic epsilon was significantly decreased during the acute phase of Kawasaki disease. This may be a result of myocardial swelling from myocarditis during the acute phase of the disease.
Jeong Jin Yu; Hyung Soon Choi; Yong Beom Kim; Jae Sung Son; Young-Hwue Kim; Jae-Kon Ko; In-Sook Park
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study     Date:  2010-04-20
Journal Detail:
Title:  Pediatric cardiology     Volume:  31     ISSN:  1432-1971     ISO Abbreviation:  Pediatr Cardiol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-27     Completed Date:  2010-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  807-12     Citation Subset:  IM    
Division of Pediatric Cardiology, Asan Medical Center, College of Medicine, University of Ulsan, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, South Korea.
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MeSH Terms
Acute Disease
Child, Preschool
Disease Progression
Echocardiography, Doppler / methods*
Follow-Up Studies
Heart Atria / physiopathology,  ultrasonography*
Heart Ventricles / physiopathology,  ultrasonography*
Mucocutaneous Lymph Node Syndrome / complications,  ultrasonography*
Myocardial Contraction / physiology*
Myocarditis / etiology,  physiopathology,  ultrasonography*
Reproducibility of Results
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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