Document Detail

Analgesic efficacy of intracapsular and intra-articular local anaesthesia for knee arthroplasty.
MedLine Citation:
PMID:  20586748     Owner:  NLM     Status:  MEDLINE    
The optimal site for wound delivery of local anaesthetic after total knee arthroplasty is undetermined. Sixty patients having total knee arthroplasty received intra-operative infiltration analgesia with ropivacaine 0.2% and were then were randomly assigned to receive either intracapsular or intra-articular catheters with 20 ml ropivacaine 0.5% given at 6 h and again at 24 h, postoperatively. Analgesic efficacy was assessed for 3 h after each injection, using a visual analogue score, where 0 = no pain and 100 = worst pain. There was no statistically significant difference between groups. Maximum pain relief (median (IQR [range])) at rest observed in the 3 h after the 6 and 24 h postoperative injections was 17 (7-31 [0-80]) and 10 (4-27 [0-50]) p = 0.27 for 6-9 h; and 17 (7-33 [0-100]) and 13 (3-25 [0-72]) p = 0.28 for 24-27 h, for intracapsular and intra-articular, respectively. Intracapsular local anaesthetic has similar analgesic efficacy to intra-articular after total knee arthroplasty.
L Ø Andersen; H Husted; B B Kristensen; K S Otte; L Gaarn-Larsen; H Kehlet
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anaesthesia     Volume:  65     ISSN:  1365-2044     ISO Abbreviation:  Anaesthesia     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2011-01-04     Completed Date:  2011-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  904-12     Citation Subset:  AIM; IM    
Copyright Information:
© 2010 The Authors. Journal compilation © 2010 The Association of Anaesthetists of Great Britain and Ireland.
Department of Anaesthesiology, Hvidovre Hospital, Denmark.
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MeSH Terms
Aged, 80 and over
Anesthetics, Local / administration & dosage*
Arthroplasty, Replacement, Knee*
Double-Blind Method
Injections, Intra-Articular
Middle Aged
Pain Measurement / methods
Pain, Postoperative / prevention & control*
Prospective Studies
Reg. No./Substance:
0/Anesthetics, Local

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