Document Detail

Analgesic abuse and personality characteristics.
MedLine Citation:
PMID:  1248916     Owner:  NLM     Status:  MEDLINE    
The Freiburg Personality Inventory (FPI) was mailed to a group of 880 female industrial workers who were participating in a 5-year prospective study aimed at elucidating eventual renal toxity of phenacetin-containing analgesics. 338 completely filled in test-sheets were returned. The study sample was divided into five sub-groups according to the amount of drug which could be located. 1. Consumers who had a positive test for analgesic-intake in at least one urine sample (paracetamol = N-acetyl-p-aminophenol as principal metabolit of phenacetin),N = 65.2. "High intakers", paracetamol values over 0.499 o.D. (o.D. = optical density in the spectrophotometric determination of paracentamol [total of three tests]), N = 73.3. "Medium intakers", paracetamol values 0.200-0.499 o.D. (total of three tests), N = 25.4. "Low intakers", paracetamol values 0.049-0.199 oD., N = 84.5. "None-consumers" with negative urine tests, N = 199. It was shown that for some personality features, consumers could be distinguished from non-consumers and "high intakers" from "low intakers", but not "low intakers" from non-consumers nor "high intakers" from "medium intakers". The areas contributing mainly to differentiation were general psychosomatic disturbance, irritability tinged with dysphoria, psychosocial and emotional immaturity, and lability. The importance of early registration is consequently demonstrated.
V Hobi; D Ladewig; U C Dubach; Miest P-Ch; T Ehrensberger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of clinical pharmacology and biopharmacy     Volume:  13     ISSN:  0340-0026     ISO Abbreviation:  Int J Clin Pharmacol Biopharm     Publication Date:  1976 Jan 
Date Detail:
Created Date:  1976-04-23     Completed Date:  1976-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505527     Medline TA:  Int J Clin Pharmacol Biopharm     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  36-41     Citation Subset:  IM    
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MeSH Terms
Middle Aged
Personality Inventory
Substance-Related Disorders*
Reg. No./Substance:

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