Document Detail

Anal canal pressure after ileal pouch-anal anastomosis with strengthened internal anal sphincter.
MedLine Citation:
PMID:  15622579     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: The aim of sphincter-saving operative techniques and creation of intestinal reservoirs is to improve the quality of life for patients with restorative prococolectomy. METHODS: In this study, 48 consecutive patients (19 males and 29 females of ages between 19 and 55 years; mean age, 35.52 years) with ulcerative colitis and familial adenomatous polyposis underwent ileal pouch-anal anastomosis after proctocolectomy in 1986 to 2002. In 26 patients (54.17 percent of the cases), 10 males and 16 females, ileal pouch-anal anastomosis was performed after a modified surgical technique for strengthening the internal anal sphincter by creation of a smooth muscle cuff through plication of a mucosectomized segment of residual rectum. Basal resting anal canal pressure and pressure after voluntary contraction were recorded preoperatively, one month after surgery, and every six months for two years. RESULTS: One month after the operation manometric results showed significantly higher values of resting pressure in patient with a plicated rectal segment than values measured preoperatively (P < 0.001). This effect was absent after the standard ileal pouch-anal anastomosis. With the rectal plication technique, basal pressure increased from a preoperative value of 69 +/- 6 mmHg up to 80 +/- 6 mmHg at the end of the second postoperative year (P < 0.001). CONCLUSIONS: We concluded that ileal pouch-anal anastomosis with rectal plication perhaps improved sphincter function. The operative technique did not affect anal squeeze pressure. Patients quality of life was improved for those undergoing the modified ileal pouch-anal anastomosis.
Georgi L Kobakov; Daniel V Kostov; Temelko D Temelkov
Related Documents :
9655689 - Interaction between neurokinin a, vip, prostanoids, and enteric nerves in regulation of...
9052509 - Effects of omeprazole on mechanisms of gastroesophageal reflux in childhood.
9733609 - Choledochosphincter inhibitory reflex: identification of the reflex in dogs and its sig...
11077329 - Antral compensation after proximal gastric vagotomy.
24744069 - Extensive warfarin-induced skin necrosis successfully treated with negative pressure wo...
3348529 - Anal sphincter pressure and the rectosphincteric reflex in the dog.
16530899 - Focal spinal arachnoiditis increases subarachnoid space pressure: a computational study.
12030799 - Role of tachykininergic and cholinergic pathways in modulating canine gastric tone and ...
22955729 - Red wine and cardiovascular health.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diseases of the colon and rectum     Volume:  47     ISSN:  0012-3706     ISO Abbreviation:  Dis. Colon Rectum     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-28     Completed Date:  2005-02-01     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372764     Medline TA:  Dis Colon Rectum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1868-73     Citation Subset:  IM    
Clinic of General and Operative Surgery, St. Marina University Hospital of Varna, Varna, Bulgaria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenomatous Polyposis Coli / surgery*
Anal Canal / physiology*,  surgery*
Anastomosis, Surgical
Colitis, Ulcerative / surgery*
Colonic Pouches*
Ileum / surgery*
Middle Aged
Proctocolectomy, Restorative*
Quality of Life
Rectum / surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Why do anal wounds heal adequately? A study of the local immunoinflammatory defense mechanisms.
Next Document:  Treatment for horseshoe fistulas-in-ano with primary closure of the internal fistula opening: a clin...