| Anaesthetic-related occurrence of early ventricular arrhythmias during acute myocardial ischaemia in rats. | |
| | |
MedLine Citation:
|
PMID: 2480088 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The cardiovascular responses of rats anaesthetised with different anaesthetic agents to acute coronary artery ligation were studied. Before thoracotomy, urethane-anaesthetised animals exhibited significantly lower blood pressures. Ligation of the left coronary artery induced a high incidence of ventricular tachycardia or fibrillation in rats anaesthetised with pentobarbitone, urethane, or ether inhalation followed by chloralose. Ketamine-anaesthetised animals had a significantly lower incidence of ventricular arrhythmias. The mortality rate was also lower, though not statistically significant. However, all groups of rats showed essentially similar blood pressure and heart rate changes following coronary artery ligation as well as the time of onset of ventricular tachycardia or fibrillation. The findings demonstrate the influence of anaesthetics on the occurrence of early ventricular arrhythmias following acute coronary artery ligation in rats. |
| | |
Authors:
|
S Dai |
Related Documents
:
|
12481928 - Early myocardial fibrosis is associated with depletion of vasoactive intestinal peptide... 16513418 - Stabilization of hypoxia inducible factor rather than modulation of collagen metabolism... 21513188 - Touching my left elbow: the anatomical structure of the body affects the illusion of se... 10892658 - [arg8]-vasopressin-induced responses on coronary and mesenteric arteries of rats with m... 11139928 - Diagnostic value of stored electrograms in single-lead vdd systems. 8304808 - Cumulative enzyme release as a measure of infarct size in patients with acute myocardia... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Archives internationales de physiologie et de biochimie Volume: 97 ISSN: 0003-9799 ISO Abbreviation: Arch. Int. Physiol. Biochim. Publication Date: 1989 Oct |
Date Detail:
|
Created Date: 1990-01-04 Completed Date: 1990-01-04 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0405355 Medline TA: Arch Int Physiol Biochim Country: BELGIUM |
Other Details:
|
Languages: eng Pagination: 341-6 Citation Subset: IM |
Affiliation:
|
Department of Pharmacology, Faculty of Medicine, University of Hong Kong. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anesthesia* Animals Arrhythmias, Cardiac / etiology* Blood Pressure Chloralose / pharmacology Coronary Disease / complications* Coronary Vessels Ether, Ethyl / pharmacology Heart Rate Ligation Male Pentobarbital / pharmacology Rats Rats, Inbred Strains Urethane / pharmacology |
| Chemical | |
Reg. No./Substance:
|
15879-93-3/Chloralose; 51-79-6/Urethane; 60-29-7/Ether, Ethyl; 76-74-4/Pentobarbital |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Alterations of energy metabolism induced by hexadecane in mice.
Next Document: Effect of hypo and hyperprolactinemia on the testicular maturation of Wistar rats during puberal tra...