Document Detail

Anaesthetic management of patients with pre-eclampsia/eclampsia and perinatal outcome.
MedLine Citation:
PMID:  19504406     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study examined risk factors for perinatal mortality associated with anaesthesia for caesarean delivery in patients with pre-eclampsia/eclampsia. The study is apt because perinatal mortality rate is one of the indicators of health status of pregnant women, new mothers and their newborns. The information obtained may help to assess changes in public health policy and practise amongst women of child-bearing age. AIM: The role of anaesthesia in perinatal outcome in pre-eclamptics. METHODS AND MATERIALS: The hospital records (cases notes, labour ward and newborn special care unit and theatre records) of patients with pre-eclampsia/eclampsia, which had caesarean delivery and their babies at the University of Nigeria Teaching hospital (UNTH), Enugu, Nigeria from July 1998 to June 2006, were retrospectively reviewed. The term perinatal mortality refers to stillbirths and neonatal deaths within 7 days of birth. RESULTS: There were a total of 6798 deliveries and 1579 women delivered through caesarean section. Of these, 196 were patients with pre-eclampsia/eclampsia. There were a total of 19 stillbirths (9%) and 19 (9%) early neonatal deaths in the pre-eclampsia/eclampsia group going a perinatal mortality of 180/1000 births. Amongst these women, 157 delivered under general anaesthesia, 34 under spinal anaesthesia and five under epidural block. Of the 38 perinatal deaths, 30 delivered by general anaesthesia and eight by regional anaesthesia. CONCLUSION: Pre-eclampsia/eclampsia continues to be a cause of foetal loss in the developing world even where essential obstetric services are available. Early onset management of severe pre-eclampsia with maintenance of adequate placental perfusion during anaesthesia may result in lower perinatal deaths.
Ugochukwu Vincent Okafor; Efena Russ Efetie; Wilson Igwe; Obioma Okezie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  22     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-11-20     Completed Date:  2010-02-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  688-92     Citation Subset:  IM    
Department of Anaesthesia, University of Nigeria Teaching Hospital, Enugu, Enugu State, Nigeria.
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MeSH Terms
Anesthesia, Obstetrical*
Cesarean Section
Eclampsia / therapy*
Gestational Age
Infant Mortality
Infant, Newborn
Nigeria / epidemiology
Pre-Eclampsia / therapy*
Pregnancy Outcome*
Retrospective Studies
Stillbirth / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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