Document Detail

Anaesthesia, perioperative management and outcome of correction of extrahepatic biliary atresia in the infant: a review of 50 cases in the King's College Hospital series.
MedLine Citation:
PMID:  11119190     Owner:  NLM     Status:  MEDLINE    
Extrahepatic biliary atresia (EHBA) is an uncommon condition presenting in the first few weeks of life. It has an incidence of 0. 5-1 per 10 000 live births and is the end result of a destructive inflammatory process involving the extrahepatic biliary system of unknown aetiology occurring in utero. The net result is neonatal jaundice due to bile stasis, with subsequent hepatocellular damage and cirrhosis. In the untreated, patient death is inevitable within 2 years. Precise diagnosis (or exclusion) of EHBA in the persistently jaundiced infant must be made urgently and major surgery (hepatic portoenterostomy: Kasai procedure) carried out as soon as possible, preferably before 6-8 weeks of age. This review is concerned with anaesthesia for correction of EHBA in 50 consecutive patients and also outlines the experience gained in the largest European centre for correction of EHBA where the number of cases now approaches 500.
D W Green; E R Howard; M Davenport
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  10     ISSN:  1155-5645     ISO Abbreviation:  Paediatr Anaesth     Publication Date:  2000  
Date Detail:
Created Date:  2001-01-16     Completed Date:  2001-02-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  581-9     Citation Subset:  IM    
Department of Anaesthetics and Intensive Care, King's College Hospital, Denmark Hill, London SE5 9RS, UK.
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MeSH Terms
Anesthesia* / methods
Biliary Atresia / diagnosis,  surgery*
Diagnosis, Differential
Infant, Newborn
Pain, Postoperative / therapy
Portoenterostomy, Hepatic
Postoperative Care
Treatment Outcome

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