Document Detail

Anaesthesia for laparoscopy: alfentanil and fentanyl compared.
MedLine Citation:
PMID:  6412612     Owner:  NLM     Status:  MEDLINE    
A double blind comparison was made between alfentanil and fentanyl as analgesic components of anaesthesia. Sixty-six women undergoing laparoscopy received methohexitone, alcuronium, nitrous oxide and oxygen, with either alfentanil 0.75 mg or fentanyl 0.25 mg. Ten of the patients who received alfentanil and 1 patient who received fentanyl required supplementation of anaesthesia by enflurane. Recovery from anaesthesia was similar in the two groups of patients though the onset of spontaneous breathing occurred more quickly after alfentanil (P less than 0.002). The injection of fentanyl was followed by a fall in BP (P less than 0.05) and the mean minimum value for pulse rate occurring after fentanyl was slower than after alfentanil (P less than 0.05).
B Kay; A T Cohen; F Shaw; T E Healy
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Annals of the Royal College of Surgeons of England     Volume:  65     ISSN:  0035-8843     ISO Abbreviation:  Ann R Coll Surg Engl     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1983-10-08     Completed Date:  1983-10-08     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  7506860     Medline TA:  Ann R Coll Surg Engl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  316-7     Citation Subset:  IM    
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MeSH Terms
Anesthesia, General*
Anesthesia, Intravenous*
Clinical Trials as Topic
Double-Blind Method
Fentanyl* / analogs & derivatives*
Random Allocation
Time Factors
Reg. No./Substance:
0/Analgesics; 437-38-7/Fentanyl; 71195-58-9/Alfentanil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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