| Anaesthesia and angiotensin-converting enzyme inhibitors. The effect of enalapril on peri-operative cardiovascular stability. | |
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MedLine Citation:
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PMID: 2850747 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of enalapril pretreatment on the haemodynamic response to tracheal intubation and surgical stimulation has been studied in 22 patients. Enalapril 5 mg given 4 hours before operation was associated with a significant reduction in the pressor response associated with intubation (p less than 0.05) and surgical stimulation (p less than 0.005) compared with control. Heart rate changes were similar in the two groups. The role of the renin-angiotensin system in relation to the pressor response to sympathetic stimulation is discussed and it is concluded that angiotensin-converting enzyme inhibitors may help improve peri-operative cardiovascular stability. |
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Authors:
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A P Yates; D N Hunter |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Anaesthesia Volume: 43 ISSN: 0003-2409 ISO Abbreviation: Anaesthesia Publication Date: 1988 Nov |
Date Detail:
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Created Date: 1989-02-17 Completed Date: 1989-02-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370524 Medline TA: Anaesthesia Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 935-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Anaesthesia, University College Hospital, London. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anesthesia, General* Enalapril / therapeutic use* Female Hemodynamics / drug effects Humans Hypertension / prevention & control* Intubation, Intratracheal Premedication* Renin-Angiotensin System / drug effects Surgical Procedures, Operative Time Factors |
| Chemical | |
Reg. No./Substance:
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75847-73-3/Enalapril |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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