Document Detail

Anaerobic cellulitis as the result of Clostridium perfringens: a rare cause of vascular access graft infection.
MedLine Citation:
PMID:  12042743     Owner:  NLM     Status:  MEDLINE    
Infection of prosthetic vascular access grafts is the second most common complication of vascular access and represents a challenge encountered by the vascular surgeon. Anaerobic graft infections are rare. We report on a case of a prosthetic vascular access graft infection with Clostridium perfringens. To our knowledge, only one other case with an infected arteriovenous shunt caused by C perfringens has been reported. The patient, a 67-year-old woman with end-stage renal failure as the result of polycystic renal disease, was seen with an infected pseudoaneurysm at the arterial puncture site of the loop graft on the left arm. There was associated purulence at the time of operation. Surgical management consisted of complete graft removal because of the presence of small tunnel abscesses. C perfringens was found in the resected pseudoaneurysm and graft material. Infected pseudoaneurysms most likely are attributable to repetitive punctures in one small area and to a break in sterile technique. A compromised vascular supply, not infrequent in patients for hemodialysis, may lower the oxidation reduction potential, which allows anaerobic bacteria, such as C perfringens, to cause infection.
Luc G Y Claeys; Ricardo Matamoros
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  35     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-03     Completed Date:  2002-07-12     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1287-8     Citation Subset:  IM    
Department of Vascular Surgery, University Hospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany.
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MeSH Terms
Catheters, Indwelling*
Cellulitis / microbiology*
Clostridium Infections / etiology*
Clostridium perfringens*
Prosthesis-Related Infections / microbiology*
Renal Dialysis

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