| Anaerobic (bacterial) vaginosis and premalignant disease of the cervix. | |
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MedLine Citation:
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PMID: 15511897 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Nitrosamines are carcinogenic substances found in cigarette smoke, and it is known that female smokers have an increased risk of cervical carcinoma and premalignant change. Nitrosamines may also be formed due to the combination of amines and nitrites in an acidic medium. This study has shown a statistically significant association between anaerobic vaginosis which produce amines and cervical intraepithelial neoplasia 2 and 3. In addition nitrate reducing organisms are found in the acidic lower genital tract in a significant number of cases. It is therefore theoretically possible that nitrosamines may be an important agent in the development of premalignant disease of the cervix. |
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Authors:
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J W Barrington; D Linton; A O'Leary; A Blackwell; J Brick; J P Calvert |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Volume: 17 ISSN: 0144-3615 ISO Abbreviation: J Obstet Gynaecol Publication Date: 1997 Jun |
Date Detail:
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Created Date: 2004-10-29 Completed Date: 2005-04-21 Revised Date: 2005-04-25 |
Medline Journal Info:
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Nlm Unique ID: 8309140 Medline TA: J Obstet Gynaecol Country: England |
Other Details:
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Languages: eng Pagination: 383-5 Citation Subset: - |
Affiliation:
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Department of Obstetrics and Gynaecology, Singleton Hospital, Swansea, UK. |
Export Citation:
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Descriptor/Qualifier:
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| Comments/Corrections | |
Comment In:
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J Obstet Gynaecol. 1998 Mar;18(2):207; author reply 207
[PMID:
15512059
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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