| Anaemia in the first but not in the second or third trimester is a risk factor for low birth weight. | |
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MedLine Citation:
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PMID: 12765667 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess pregnancy outcome in women with anaemia during pregnancy. METHODS: The study design involved a retrospective chart review of all women registering for prenatal care in the area of Kuopio University Hospital between 1990 and 2000. A haemoglobin concentration below 100g/l was used as a cutoff for anaemia and affected women (N=597) were stratified by the trimester at which anaemia was diagnosed. Multiple regression analysis was used to compare obstetric outcomes in the study groups and in non-anaemic women (N=22,202). RESULTS: The frequency of anaemia was 2.6%, with 0.3% occurring in the first trimester. After controlling for confounding factors, anaemia detected in the first trimester was associated with low-birth-weight infants (OR=3.14, 95% CI: 1.35-7.28) whereas the mid- and third-trimester anaemia groups showed no significantly different outcomes when compared with the non-anaemic women. First trimester anaemia was not significantly associated with small birth weight for gestational age (OR=0.98, 95% CI: 0.41-2.17) or with premature delivery <37 weeks (OR=1.80, 95% CI: 0.72-4.49). CONCLUSIONS: Maternal anaemia detected in the first trimester is associated with low birth weight. |
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Authors:
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Henna Hämäläinen; Katja Hakkarainen; Seppo Heinonen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical nutrition (Edinburgh, Scotland) Volume: 22 ISSN: 0261-5614 ISO Abbreviation: Clin Nutr Publication Date: 2003 Jun |
Date Detail:
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Created Date: 2003-05-26 Completed Date: 2003-12-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8309603 Medline TA: Clin Nutr Country: Scotland |
Other Details:
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Languages: eng Pagination: 271-5 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Kuopio University Hospital, Finland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anemia / blood*, epidemiology Female Finland / epidemiology Hemoglobins / analysis Humans Infant, Low Birth Weight* Infant, Newborn Infant, Premature Pregnancy / blood* Pregnancy Complications* Pregnancy Outcome* Pregnancy Trimester, First / blood Pregnancy Trimester, Second / blood Pregnancy Trimester, Third / blood Retrospective Studies Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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