Document Detail

Anabolic steroids in athelics: crossover double-blind trial on weightlifters.
MedLine Citation:
PMID:  125133     Owner:  NLM     Status:  MEDLINE    
Thirteen experienced male weightlifters taking high-protein diets and regular exercise took part in a double-blind crossover trial of methandienone 10 or 25 mg/day to seeif the drug improved athletic performance. Their improvemments were significantly greater on methandienone than on placebo; their body weights rose (though this seemed to be associated with water retention); and systolic blood pressure rose significantly. Methandienone caused many side effects, and three men had to withdraw because of them. All side effects disappeared after the drug was stopped. Anabolic steroids are effective only when given combination with exercise and high-protein diet. We deprecate their use in athletics but can suggest no way of stopping it.
D L Freed; A J Banks; D Longson; D M Burley
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British medical journal     Volume:  2     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1975 May 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2010-09-01    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  471-3     Citation Subset:  AIM; IM    
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MeSH Terms
Acne Vulgaris / chemically induced
Alanine Transaminase / blood
Anabolic Agents / pharmacology*
Blood Pressure / drug effects
Body Weight / drug effects
Cholesterol / blood
Clinical Trials as Topic
Dietary Proteins
Headache / chemically induced
Hypertension / chemically induced
Methandrostenolone / administration & dosage,  adverse effects,  pharmacology
Physical Exertion / drug effects*
Sexual Behavior / drug effects
Sports Medicine*
Reg. No./Substance:
0/Anabolic Agents; 0/Dietary Proteins; 0/Placebos; 57-88-5/Cholesterol; 72-63-9/Methandrostenolone; EC Transaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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