| Amyotrophic lateral sclerosis with ophthalmoplegia. A clinicopathologic study. | |
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MedLine Citation:
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PMID: 485889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ophthalmoplegia is rarely observed in patients with amyotrophic lateral sclerosis (ALS). We describe a patient with ALS in whom ophthalmoplegia, initially appearing midway in her course, progressed to total paralysis of extraocular movements by the time of death. In addition to the usual postmortem findings of ALS in the brain stem and spinal cord, there was extensive neuronal loss and gliosis involving the caudal portions of the dorsal and intermediate components of the oculomotor nuclei, the caudal part of the trochlear nuclei, and the abducens nuclei. This represents the first detailed report of the findings in the nuclei of cranial nerves III, IV, and VI in a patient with ALS and ophthalmoplegia. |
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Authors:
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D G Harvey; R M Torack; H E Rosenbaum |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of neurology Volume: 36 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1979 Oct |
Date Detail:
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Created Date: 1979-11-28 Completed Date: 1979-11-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 615-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amyotrophic Lateral Sclerosis
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pathology* Brain / pathology* Brain Stem / pathology Cell Nucleus / pathology Cerebral Cortex / pathology Female Gliosis / pathology Humans Middle Aged Ophthalmoplegia / pathology* Spinal Cord / pathology |
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