| Amyotrophic lateral sclerosis versus cervical spondylotic myelopathy: a study using transcranial magnetic stimulation with recordings from the trapezius and limb muscles. | |
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MedLine Citation:
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PMID: 10825710 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We report an electrophysiological method to differentiate amyotrophic lateral sclerosis (ALS) from cervical spondylotic myelopathy (CSM). METHODS: Motor evoked potentials (MEPs) by transcranial magnetic stimulation were investigated in patients with ALS (n=10) and CSM (n=9). In addition to limb MEPs using the triple stimulation technique (TST) at upper limbs, MEPs recorded from trapezius muscles were compared with those obtained from 23 normal subjects. The parameters studied were: central motor conduction time, amplitude ratio and, for the trapezius, the interside asymmetry. RESULTS: Whereas limb MEPs were abnormal in most ALS and CSM patients (17/19), trapezius MEPs were abnormal in all ALS patients, and normal in 8 out of 9 CSM patients. CONCLUSION: Recording of trapezius MEPs is a valuable addition to the limb MEPs study, since it distinguishes ALS from SCM in most patients. |
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Authors:
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A Truffert; K M Rösler; M R Magistris |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: 111 ISSN: 1388-2457 ISO Abbreviation: Clin Neurophysiol Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-07-14 Completed Date: 2000-07-14 Revised Date: 2008-09-10 |
Medline Journal Info:
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Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 1031-8 Citation Subset: IM |
Affiliation:
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Department of Clinical Neurology, University Hospital, Geneva, Switzerland. andre.truffert@hcuge.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Arm / innervation Cervical Vertebrae* Diagnosis, Differential Evoked Potentials, Motor / physiology* Female Humans Male Middle Aged Motor Neuron Disease / diagnosis*, physiopathology* Muscle, Skeletal / innervation, physiology, physiopathology* Neural Conduction Reference Values Spinal Osteophytosis / diagnosis*, physiopathology* Transcranial Magnetic Stimulation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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