| Amyotrophic lateral sclerosis: prospective study on respiratory parameters. | |
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MedLine Citation:
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PMID: 20464296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To verify how efficient respiratory parameters are in the follow-up of subjects with amyotrophic lateral sclerosis (ALS) and to observe possible correlations between respiratory and nutritional functions. METHOD: Sixteen patients with probable or defined ALS were selected and evaluated over eight months using the following respiratory parameters: spirometry, maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), arterial gasometry and pulse oximetry; and nutritional parameters such as body mass index (BMI) and percentage weight loss. RESULTS: P(a)CO(2) was a significant parameter to follow up disease evolution (p=0.051). There was significant correlation between MIP and MEP (r: 0.83); BMI and MIP (r: 0.70); BMI and MEP (r: 0.72); pulse oximetry and forced vital capacity (r: 0.57). CONCLUSION: P(a)CO(2) was shown to be an efficient and significant parameter in the measurement of respiratory impairment; the correlations among MIP, MEP and BMI indicated that these are significant parameters for periodic clinical evaluation. |
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Authors:
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Sara Regina Meira Almeida; Luciano Bruno C Silva; Carlos Alberto M Guerreiro; Anamarli Nucci |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Arquivos de neuro-psiquiatria Volume: 68 ISSN: 1678-4227 ISO Abbreviation: Arq Neuropsiquiatr Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-13 Completed Date: 2010-07-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0125444 Medline TA: Arq Neuropsiquiatr Country: Brazil |
Other Details:
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Languages: eng Pagination: 258-62 Citation Subset: IM |
Affiliation:
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Department of Neurology, School of Medical Sciences, University of Campinas, Campinas, SP, Brazil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amyotrophic Lateral Sclerosis / complications* Body Mass Index Cross-Sectional Studies Female Humans Male Middle Aged Nutritional Status* Prospective Studies Respiration Disorders / diagnosis*, etiology Respiratory Function Tests / methods |
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