Document Detail


Amyotrophic lateral sclerosis in a patient with fragile X syndrome.
MedLine Citation:
PMID:  2300265     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fragile X syndrome is a common cause of mental retardation. We report the clinical and pathologic features of a patient with fragile X syndrome who developed amyotrophic lateral sclerosis (ALS) at a relatively young age. Although the occurrence of these 2 diseases could be a mere coincidence, the development of ALS in this patient might be related to the chromosomal aberration of fragile X syndrome.
Authors:
H B Desai; J Donat; M H Shokeir; D G Munoz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  40     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-03-15     Completed Date:  1990-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  378-80     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology, University Hospital, Saskatoon, Saskatchewan, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amyotrophic Lateral Sclerosis / genetics,  pathology*
Brain / pathology
Fragile X Syndrome / genetics,  pathology*
Humans
Male
Sex Chromosome Aberrations / pathology*
Spinal Cord / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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