Document Detail

Amyloid vascular disease: cord-like thickening of mucocutaneous arteries, intermittent claudication and angina in a case with underlying myelomatosis.
MedLine Citation:
PMID:  7387902     Owner:  NLM     Status:  MEDLINE    
A patient with established myelomatosis and an IgG paraproteinaemia presented with intermittent claudication. Indurated cord-like structures were noted on the dorsum of the right hand and the buccal surface of the lower lip, and biopsy of the hand lesion revealed massive amyloid deposition within the wall of an artery. Cord-like thickening of mucocutaneous arteries as a presenting sign of systemic amyloidosis in the absence of glossomegaly or other cutaneous lesions has not been reported previously. The presence of intermittent claudication and angina suggested that amyloid involvement of large arteries was extensively distributed.
S M Breathnach; G C Wells
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  102     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-09-26     Completed Date:  1980-09-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  591-5     Citation Subset:  IM    
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MeSH Terms
Amyloidosis / etiology*
Angina Pectoris / etiology*
Arterial Occlusive Diseases / etiology*
Immunoglobulin G
Intermittent Claudication / etiology*
Middle Aged
Multiple Myeloma / complications*
Paraproteinemias / complications
Reg. No./Substance:
0/Immunoglobulin G

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