Document Detail

Amyloid arthropathy mimicking seronegative rheumatoid arthritis in multiple myeloma: case reports and review of the literature.
MedLine Citation:
PMID:  19922335     Owner:  NLM     Status:  MEDLINE    
We report two patients who suffered from symmetrical polyarthritis simulating rheumatoid arthritis. Acute phase response was almost within normal limits, and autoantibodies including rheumatoid factor were negative. Both of them were diagnosed as having amyloid arthropathy (AmyA) secondary to kappa multiple myeloma based on deposition of kappa-light chain-immunoreactive amyloid in biopsied tissue and Bence Jones protein in urine. Systemic AL amyloidosis may be important in the differential diagnosis of chronic polyarthralgia.
Nilüfer Alpay; Bahar Artim-Esen; Sevil Kamali; Ahmet Gül; Sevgi Kalayoğlu-Beşişik
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis     Volume:  16     ISSN:  1744-2818     ISO Abbreviation:  Amyloid     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-20     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433802     Medline TA:  Amyloid     Country:  England    
Other Details:
Languages:  eng     Pagination:  226-31     Citation Subset:  IM    
Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
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MeSH Terms
Amyloidosis / diagnosis*,  metabolism,  urine
Arthritis, Rheumatoid / diagnosis*,  etiology,  pathology
Bence Jones Protein / urine
Joint Diseases / diagnosis*,  etiology*
Middle Aged
Multiple Myeloma / complications*,  metabolism,  physiopathology*
Reg. No./Substance:
9006-99-9/Bence Jones Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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