| Amygdala gray matter concentration is associated with extraversion and neuroticism. | |
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MedLine Citation:
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PMID: 16272876 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using high-resolution magnetic resonance imaging and voxel-based morphometry in 41 healthy individuals, this study evaluated the association between the personality traits of extraversion and neuroticism, on the one hand, and individual differences in localized brain volume and gray matter concentration, on the other, with a special focus on the amygdala. Extraversion was positively correlated with gray matter concentration in the left amygdala, whereas neuroticism was negatively correlated with gray matter concentration in the right amygdala. Given that neuroticism is a risk factor for depression, our finding offers one explanation as to why prior structural imaging studies of depressed patients (which did not control for personality) produced conflicting findings. Furthermore, our data are consistent with the view that amygdala reduction seen in depressed patients precedes the onset of the disease, rather than being a consequence of the illness. |
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Authors:
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Kazufumi Omura; R Todd Constable; Turhan Canli |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Neuroreport Volume: 16 ISSN: 0959-4965 ISO Abbreviation: Neuroreport Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-11-07 Completed Date: 2006-01-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9100935 Medline TA: Neuroreport Country: England |
Other Details:
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Languages: eng Pagination: 1905-8 Citation Subset: IM |
Affiliation:
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Department of Psychology, Stony Brook University, Stony Brook, New York 11794-2500, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amygdala / pathology*, physiology* Extraversion (Psychology)* Female Humans Magnetic Resonance Imaging Male Neurotic Disorders / pathology*, physiopathology* |
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