| Amrinone--a new inotropic agent in chronic resistant congestive cardiac failure. | |
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MedLine Citation:
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PMID: 6949545 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient with severe cardiac failure due to idiopathic congestive cardiomyopathy resistant to conventional therapy, responded to amrinone, a new non-glycosidic non-catecholamine positive inotropic agent. Amrinone produced significant haemodynamic improvement during both intravenous and oral administration. Thrombocytopaenia, however, was induced, necessitating cessation of the drug. Amrinone is a promising, orally effective inotropic agent for patients with refractory congestive cardiac failure, but is limited to its tendency to cause thrombocytopaenia. |
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Authors:
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P J Robinson; R Lvoff; B Chong; P A Barrett |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Australian and New Zealand journal of medicine Volume: 11 ISSN: 0004-8291 ISO Abbreviation: Aust N Z J Med Publication Date: 1981 Dec |
Date Detail:
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Created Date: 1982-04-12 Completed Date: 1982-04-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1264322 Medline TA: Aust N Z J Med Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 666-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Aminopyridines / administration & dosage, adverse effects, therapeutic use* Amrinone Cardiotonic Agents / administration & dosage, adverse effects, therapeutic use* Heart Failure / drug therapy* Hemodynamics / drug effects Humans Injections, Intravenous Male Middle Aged Myocardial Contraction / drug effects Thrombocytopenia / chemically induced |
| Chemical | |
Reg. No./Substance:
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0/Aminopyridines; 0/Cardiotonic Agents; 60719-84-8/Amrinone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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