Document Detail

Amputation prevention in a high-risk population through comprehensive wound-healing protocol.
MedLine Citation:
PMID:  2802960     Owner:  NLM     Status:  MEDLINE    
This study included patients who presented with at least one chronic nonhealing ulcer and had been told by their referring physician that they would require amputation at the transmetatarsal level or higher. Hospital records of all patients seen in a comprehensive wound-healing clinic from August 1984 through January 1986 were reviewed. Twenty-four patients with 27 lower extremity ulcers were identified. An aggressive clinical wound care protocol, including arterial revascularization, control of infection, wound debridement, protective orthotics, and use of topically applied autologous Platelet-Derived Wound Healing Formula, was used to heal these chronic ulcers. With follow-up time ranging from 12 to 22 months, complete wound healing was obtained in 18 of 24 patients (75%), and limb salvage was obtained in 20 of 24 patients (83%). Of the 24 patients, 18 (75%) achieved wound healing and a functional limb; 16 of the 18 (67%) were ambulatory, and two (8%) had a functional limb for transfers, but were not ambulatory due to preexisting stroke. We conclude that an aggressive, comprehensive amputation intervention program can prevent the emotional, functional, and economic costs of limb loss in most high-risk patients.
M M Doucette; C Fylling; D R Knighton
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  70     ISSN:  0003-9993     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-11-06     Completed Date:  1989-11-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  780-5     Citation Subset:  AIM; IM    
Department of Surgery and Physical Medicine, Minneapolis Veterans Medical Center.
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MeSH Terms
Leg / blood supply
Middle Aged
Retrospective Studies
Risk Factors
Vascular Diseases / surgery*
Wound Healing*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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