Document Detail


Amplitude modulation patterns of local field potentials reveal asynchronous neuronal populations.
MedLine Citation:
PMID:  17715359     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Neural oscillations, which appear in several areas of the nervous system and cover a wide frequency range, are a prominent issue in current neuroscience. Extracellularly recorded oscillations are generally thought to be a manifestation of a neural population with synchronized electrical activity resulting from coupling mechanisms. The vertebrate olfactory neuroepithelium exhibits beta-band oscillations, termed peripheral waves (PWs), in their population response to odor stimulation. Here, we examine PWs in the channel catfish and propose that their properties could be explained as the superposition of asynchronous oscillators. Our model shows that the intriguing random pattern of amplitude-modulated PWs could be explained by Rayleigh fading, an interference phenomenon well known in physics and recognizable using statistical methods and signal analysis. We are proposing a mathematical fingerprint to characterize neural signals generated by the addition of random phase oscillators. Our interpretation of PWs as arising from asynchronous oscillators could be generalized to other neuronal populations, because it suggests that neural oscillations, detected in local field potential recordings within a narrow frequency band, do not necessarily originate from synchronization events.
Authors:
Javier Díaz; Pablo Razeto-Barry; Juan-Carlos Letelier; John Caprio; Juan Bacigalupo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  27     ISSN:  1529-2401     ISO Abbreviation:  J. Neurosci.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-23     Completed Date:  2007-09-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9238-45     Citation Subset:  IM    
Affiliation:
Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile 7800023.
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Clocks / physiology*
Electric Stimulation / methods
Ictaluridae / anatomy & histology
Mathematics
Membrane Potentials / drug effects,  physiology*
Models, Biological
Neurons / physiology*
Odors
Olfactory Bulb / cytology
Patch-Clamp Techniques

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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